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The following slides accompanied a presentation delivered at ASHA’s Clinical Practice Research Institute. Precision and Accuracy Adapted from Hulley, et al. (2007) . Just about every statistic (descriptive and inferential) is an expression of a basic ratio. In the numerator goes a measurement of the influence of the research hypothesis....

Strategies and considerations for increasing the utility of experiments by incorporating clinical relevance, social validity, and clinical significance into planning study designs

Strategies and considerations for increasing the utility of experiments by incorporating clinical relevance, social validity, and clinical significance into planning study designs Evidence Based Practice and the Knowledge Transfer Problem Within EBP, knowledge transfer refers to the adoption and usage of evidence — produced through clinical research — by clinical...

How do I establish what constitutes an important finding and how many participants do I need to detect it?

How do I establish what constitutes an important finding and how many participants do I need to detect it? The following slides accompanied a presentation delivered at ASHA’s Clinical Practice Research Institute. Overview of Group Studies of Treatment Adapted from Gallin & Ognibene (2007). A straightforward challenge in logical conclusion...

The following slides accompanied a presentation delivered at ASHA’s Clinical Practice Research Institute. Data speak, not men… “Designs have inherent rigor but not all studies using a design are rigorous” — Randy; yesterday “Illusion of strong evidence…”– Gilbert, McPeek & Mosteller, 1977 Effects of Interpretation Bias on Research Evidence (Kaptchuk,...

The following slides accompanied a presentation delivered at ASHA’s Clinical Practice Research Institute. The Logic of a Staged System of Clinical Research Let’s examine the fundamental logic underpinning a staged system of clinical research (that is easily applied to patient-oriented research) as developed in medicine. A protocol achieving status as...

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