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The following is a transcript of the presentation video, edited for clarity. My name is Sharon Yeatts, and I’m an Assistant Professor of Biostatistics with the Data Coordination Unit at MUSC. And we are responsible in many cases, as the Statistics and Data Management Center for helping to design and...
This presentation was delivered as part of a workshop session on the application of adaptive design principles to clinical trials in speech-language pathology. Ray Kent provides summary thoughts and comments on the seminar, with additional comments from Sharon Yeatts, who explored adaptive designs in greater depth in her presentation, Adaptive...
This presentation was delivered as part of a workshop session on the application of adaptive design principles to clinical trials in speech-language pathology. For an overview of adaptive designs, see Adaptive Trial Designs for the Development of Treatment Parameters. The following is a transcript of the presentation video, edited for...
This presentation was delivered as part of a workshop session on the application of adaptive design principles to clinical trials in speech-language pathology. Susan Langmore, a swallowing researcher, discusses challenges in her clinical trial, while Sharon Yeatts, a biostatistician, provides her thoughts on potential opportunities and pitfalls in integrating adaptive...
This presentation was delivered as part of a workshop session on the application of adaptive design principles to clinical trials in speech-language pathology. JoAnne Robbins, a swallowing researcher, discusses challenges in her past and current clinical trials, while Sharon Yeatts, a biostatistician, provides her thoughts on potential opportunities and pitfalls...
I’ve spent a life trying to develop tasks, that are good tasks, that actually measure what we think they measure. When I think about it, I think the one common factor going through anything that I’ve ever tried to do, I would call and other people have called the “task...
Presented at the Clinical Practice Research Institute (CPRI). Hosted by the American Speech-Language-Hearing Association Research Mentoring Network. Essential Elements 1. List the title of the proposed research, the Principal Investigator(s), and the institution(s). 2. If prior clinical trial experience is minimal, appoint clinical trial expert(s) as key personnel to help...
The following is a transcript of the presentation video, edited for clarity. I’m delighted to talk to you about NIH initiatives to improve measurement. They have some similarities between them, and I will point those out. The first one I’m going to talk about is PROMIS. I’m going to start...
Measuring and modeling outcomes when the treatment and goals are individualized to a client’s priorities and capabilities. In measuring clinical outcomes of behavioral and symptom-targeted interventions we’re looking at changing aspects of patient’s behavior, feelings, symptoms, or daily functioning. And in these cases, the treatment is goal directed and targets...
The following slides accompanied a presentation delivered at ASHA’s Clinical Practice Research Institute. Precision and Accuracy Adapted from Hulley, et al. (2007) . Just about every statistic (descriptive and inferential) is an expression of a basic ratio. In the numerator goes a measurement of the influence of the research hypothesis....
The American Speech-Language-Hearing Association (ASHA) is the national professional, scientific, and credentialing association for 241,000 members, certificate holders, and affiliates who are audiologists; speech-language pathologists; speech, language, and hearing scientists; audiology and speech-language pathology assistants; and students.
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