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Presented at the Clinical Practice Research Institute (CPRI). Hosted by the American Speech-Language-Hearing Association Research Mentoring Network. Essential Elements 1. List the title of the proposed research, the Principal Investigator(s), and the institution(s). 2. If prior clinical trial experience is minimal, appoint clinical trial expert(s) as key personnel to help...
The following is a transcript of the presentation video, edited for clarity. I’m delighted to talk to you about NIH initiatives to improve measurement. They have some similarities between them, and I will point those out. The first one I’m going to talk about is PROMIS. I’m going to start...
Measuring and modeling outcomes when the treatment and goals are individualized to a client’s priorities and capabilities. In measuring clinical outcomes of behavioral and symptom-targeted interventions we’re looking at changing aspects of patient’s behavior, feelings, symptoms, or daily functioning. And in these cases, the treatment is goal directed and targets...
The following slides accompanied a presentation delivered at ASHA’s Clinical Practice Research Institute. Precision and Accuracy Adapted from Hulley, et al. (2007) . Just about every statistic (descriptive and inferential) is an expression of a basic ratio. In the numerator goes a measurement of the influence of the research hypothesis....
The following slides accompanied a presentation delivered at ASHA’s Clinical Practice Research Institute. Data speak, not men… “Designs have inherent rigor but not all studies using a design are rigorous” — Randy; yesterday “Illusion of strong evidence…”– Gilbert, McPeek & Mosteller, 1977 Effects of Interpretation Bias on Research Evidence (Kaptchuk,...
The following slides accompanied a presentation delivered at ASHA’s Clinical Practice Research Institute. Another approach to analyzing data from group comparison studies. Instead of comparing means, dichotomize the event (outcome) of interest as “present” or “absent” in individual patients within the groups. Then compare the distribution of events in the...
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